Synthesis and Antitumor Activity of Tropolone Derivatives. 4

DOI: 10.1021/jm00384a020

Source and publish data:

Journal of Medicinal Chemistry p. 117 - 120 (1987)

Update date:2022-08-02

Topics:

Authors:

Yamato, Masatoshi

Hashigaki, Kuniko

Sakai, Junko

Kawasaki, Youko

Tsukagoshi, Shigeru

Tashiro, Tazuko

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Article abstract of DOI:10.1021/jm00384a020

Modifications of monotropolone 2 having poor potency against P388 in mice were studied. The α-ethoxy group of 2, prepared from hinokitiol and benzaldehyde diethyl acetal, was replaced with a phenolic or heteroaromatic compound by heating 2 with the approp

Full text of DOI:10.1021/jm00384a020

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