Synthesis of Furopyrimidine Derivatives via Reaction of 4-Methylpyrimidine-5-carboxylic Acids with Thionyl Chloride

DOI: 10.1055/s-1986-31502

Source and publish data:

Synthesis p. 142 - 144 (1986)

Update date:2022-07-31

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Authors:

Machon, Z.

Cieplik, J.

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Article abstract of DOI:10.1055/s-1986-31502

6-Anilino-5-carboxy-4-methyl-2-phenylpyrimidines undergo an unusual reaction with thionyl chloride to give 4-anilino-5-oxo-2-phenyl-7-thioxo-5,7-dihydrofuro<3,4-d>pyrimidines, presumably via a sulfine as intermediate.

Full text of DOI:10.1055/s-1986-31502

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