An improved synthesis of 2-diazo-1,3-diketones

DOI: 10.1055/s-1991-26416

Source and publish data:

Synthesis p. 195 - 198 (1991)

Update date:2022-08-03

Topics:

Authors:

Popic Popic

Korneev Korneev

Nikolaev

Korobitsyna

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1991-26416

The sodium hydride/dibenzo-18-crown-6 ether system was found to be an effective base for the synthesis of 1,3-diketones by the Claisen condensation. The use of potassium fluoride (with or without crown ether) as the base in diazo-transfer reactions extends this reaction to the synthesis of hindered diazo diketones. In the case of isomeric 1,3-diketones, the stereoselectivity of the process considerably rises.

Full text of DOI:10.1055/s-1991-26416

Products guided by the article

Product name:1,3-Propanedione, 2-diazo-1,3-bis(4-methylphenyl)-

Cas No:105141-03-5

R&D Labs maybe for 105141-03-5

Shenyang NovPharm Technology Co., Ltd.

Contact:.+86-24-24165786

Address:Room 306, Hongjin Mansion, No. 36-1, Wanliutang Rd., Shenhe District, Shenyang, Liaoning, P.R.C.
Engineering Research Center of Pesticide, Heilongjiang Province

Contact:+86-451-86609001

Address:No.74 of Xuefu Road, Nangang District,
Shanghai Hongbang Medical Technology CO.,. Ltd

Contact:13671516988 /18917636693

Address:Room1, No67 Building, Yongde Road369, Wujing Town, Minhang Districy, Shanghai CIty, China.
Anhui Biochem United Pharmaceutical Co., Ltd.

Contact:0086 551 5167062 / 5228268

Address:No. 30 Hongfeng Road, Hi-Tech Development Zone, Hefei (230088), China
Beijing Merson Pharmaceutical Co., Ltd

Contact:0086-10-80484934 0086-10-80484574/

Address:2nd Floor , No. 2 Building , No. 14 Houshayu Duan, Jingmi Road ,Shunyi District , Beijing 101318, P.R.China

Relevant to this article

Zirconium-catalyzed and zirconium-promoted cyclization reactions of non-conjugated dienes with alkylmagnesium halides to give cycloalkylmethylmagnesium derivatives

Doi:10.1016/s0020-1693(98)00064-4
(1998)
A NOVEL EXPEDITIOUS ENTRY INTO GIBBERELLINS. THE TOTAL SYNTHESIS OF (+/-)-GA₅

Doi:10.1016/S0040-4039(00)84359-2
(1986)
Wacker-type oxidative functionalization of β-substituted unsaturated sulfoxides

Doi:10.1016/j.tetlet.2008.06.059
(2008)
CONVERSION OF 2'-HYDROXYCHALCONES TO FLAVANONES CATALYZED BY COBALT SHIFF BASE COMPLEX

Doi:10.1016/S0040-4039(00)99344-4
(1989)
Tritylation of tetrazole and 5-substituted tetrazoles with triphenylmethanol

Doi:10.1023/A:1013849329273
(2001)
Inactivation of S-adenosyl-L-homocysteine hydrolase by 6′-cyano- 5′,6′-didehydro-6′-deoxyhomoadenosine and 6′-chloro- 6′-cyano-5′,6′-didehydro-6′-deoxyhomoadenosine. Antiviral and cytotoxic effects

Doi:10.1021/jm051023x
(2006)

Article Doi