(+/-)-(Z)-2-(aminomethyl)-1-phenylcyclopropanecarboxamide derivatives as a new prototype of NMDA receptor antagonists.

DOI: 10.1021/jm00015a019

Source and publish data:

Journal of medicinal chemistry p. 2964 - 2968 (1995)

Update date:2022-08-03

Topics:

Authors:

Shuto Shuto

Takada Takada

Mochizuki

Tsujita Tsujita

Hase Hase

Ono Ono

Shibuya Shibuya

Matsuda Matsuda

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00015a019

(+/-)-(Z)-2-(Aminomethyl)-1-phenylcyclopropane-N,N-diethylcarbo xamide (milnacipran, 1), a clinically useful antidepressant, and its derivatives were prepared by an improved method and were evaluated as NMDA receptor antagonists. Of these, milnacipran (1)

Full text of DOI:10.1021/jm00015a019

Products guided by the article

Product name:cis-2-(AMinoMethyl)-1-phenylcyclopropanecarboxylic Acid Hydrochloride

Cas No:105310-28-9

R&D Labs maybe for 105310-28-9

WUHAN WELLSONG INT'L CO.,LTD

Contact:+86-27-85733560

Address:NO.308,QINGNIAN RD.,WUHAN,CHINA
Deer Chemicals Co., Ltd.

Contact:+86-13666670345

Address:Agricultural Development Zone, Haining, Jiaxing, Zhejiang
Hebei Maison Chemical Co.,Ltd

website:http://www.maisonchem.com.cn

Contact:0086-311-83833777

Address:Leitou industrial district, xinji, shijiazhuang city, hebei province,
Shandong Dayi Chemical Co., Ltd.

website:http://www.dayi.com.cn

Contact:+86- 535-7388728. 15306386031

Address:No 1 Danya west road, Laiyang City, Shandong province
Nanjing Chemlin Chemical Co., Ltd.

website:http://www.echemlin.cn

Contact:+86-25-83697070

Address:Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China

Relevant to this article

Doi:10.1002/hlca.19610440320
(1961)
A Divergent Route for a Total Synthesis of Cyclophellitol and Epicyclophellitol from a <2.2.2>Oxabicyclic Glycoside Prepared from D-Glucal

Doi:10.1021/jo00091a004
(1994)
Synthesis and confromational analysis of the plant hormone (auxin) related 2-(indol-3-yl)ethyl and 2-phenylethyl β-D-xylopyranosides and their 2,3,4-tri-O-acetyl derivatives

Doi:10.1016/0008-6215(95)00037-T
(1995)
Microbial Transformations. 8. First Example of a Highly Enantioselective Microbiological Hydroxylation Process

Doi:10.1021/jo00243a036
(1988)
Green hydroselenation of aryl alkynes: Divinyl selenides as a precursor of resveratrol

Doi:10.3390/molecules22020327
(2017)
Ring opening complexation of nickel(II) and copper(II) by 2-phenyl-2-(2-pyridyl)imidazolidine: Synthesis, spectra and X-ray crystal structures

Doi:10.1016/j.poly.2008.04.028
(2008)

Article Doi