A Divergent Route for a Total Synthesis of Cyclophellitol and Epicyclophellitol from a Oxabicyclic Glycoside Prepared from D-Glucal

Article abstract of DOI:10.1021/jo00091a004

D-Glucal has been used for syntheses of Tatsuta's penultimate intermediate for cyclophellitol and epicyclophellitol via a 6-exo-trig radical cyclization of 2-deoxy-2-iodo-6-alkynyl glycoside, the diastereomeric mixture produced thereby being separated into two sets, each of which leads to one or other target materials.