Inhibitors of human nitric oxide synthase isoforms with the carbamidine moiety as a common structural element

Article abstract of DOI:10.1016/0968-0896(96)00148-4

Identification of potent and selective inhibitors of inducible nitric oxide synthase (NOS) is of great interest because of their therapeutic potential for treatment of diseases mediated by excess production of nitric oxide. We present here a comparison of