A Practical and Divergent Way to Trihydroxylated Pyrrolidine Derivatives as Potential Glycosidase Inhibitors via Stereoselective Intermolecular cis-Amidoalkylations

DOI: 10.1021/jo00106a021

Source and publish data:

Journal of Organic Chemistry p. 103 - 108 (1995)

Update date:2022-08-03

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Authors:

Ryu, Youngha

Kim, Guncheol

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Article abstract of DOI:10.1021/jo00106a021

A practical and divergent way from the common tartrimide 1 to trihydroxylated pyrrolidines 2a-h as potential glycosidase inhibitors has been developed. cis-Amidoalkylations on the acyliminium intermediate 5 of the corresponding TBS-protected tartaric imid

Full text of DOI:10.1021/jo00106a021

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