Journal of Medicinal Chemistry p. 826 - 835 (1995)
Update date:2022-07-29
Topics: Synthesis TLC Column chromatography Silica gel Dichloromethane Tetrahydrofuran Pyridine Dimethylformamide Refluxed Dioxane Lithium aluminium hydride Biological Evaluation Conclusion Structure Analysis Results and Discussion
Verheggen, Ilse
Aerschot, Arthur Van
Meervelt, Luc Van
Rozenski, Jef
Wiebe, Leonard
et al.
In view of the selective anti-HSV activity of 1,5-anhydro-2,3-dideoxy-2-(5-iodouracil-1-yl)-D-arabino-hexitol, a series of novel 1,5-anhydrohexitol nucleosides were synthesized and evaluated for their inhibitory activity against several viruses.The 5-iodo
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(1971)
