2,4-Diamino-5-benzylpyrimidines as antibacterial agents. 7. Analysis of the effect of 3,5-dialkyl substituent size and shape on binding to four different dihydrofolate reductase enzymes

DOI: 10.1021/jm00385a017

Source and publish data:

Journal of Medicinal Chemistry p. 348 - 356 (1987)

Update date:2022-08-05

Topics:

Authors:

Roth

Rauckman

Ferone

Baccanari

Champness

Hyde