A Method for the Preparation of Stereochemically Defined ψ Pseudodipeptides

DOI: 10.1021/jo00379a019

Source and publish data:

Journal of Organic Chemistry p. 418 - 422 (1987)

Update date:2022-08-04

Topics:: Authors:

TenBrink, Ruth E.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00379a019

A short, stereochemically defined synthesis of (2S,5S)-ψ pseudodipeptides (7a,7b,10) using commercially available, chiral amino acids has been developed.The key step of the synthesis is the intramolecular S_N2 displacement of bromine with alkoxide to give 1,4-oxazin-2-ones (6a,6b,9) that are subsequently hydrolyzed to the desired ψ pseudodipeptides.

Full text of DOI:10.1021/jo00379a019

Products guided by the article

Product name:N-<2-(R)-bromo-3-phenylpropionyl>-L-proline

Cas No:106163-49-9

R&D Labs maybe for 106163-49-9

Tianjin Jiuri New Materials Co., Ltd.

Contact:+86-22-58889220

Address:C-5/6, Vison Hill, No.1 Gonghua Road, Huayuan Hi-tech Park, Tianjin, China.
HEBEI BRANT PHARMACEUTICAL

Contact:+86-0311-84455288-844

Address:Mayu Industrial Park, Jinzhou, Hebei, China.
Chinese Peptide Company

Contact:86-571-86737118-8689

Address:No.69, 12 Street, HEDA, Hangzhou, Zhejiang, China
Dongguan Albiya Energy Science and Technology Co.,Ltd

Contact:+86-769-22181286

Address:Huanan Industial Park, Dongguan,China
ORCHID CHEMICAL SUPPLIES LTD

website:http://www.orchid-chem.com

Contact:+86-571-85395792

Address:607, North Zhongshan Road, Hangzhou 310000 China

Relevant to this article

Studies on stable diazoalkanes as potential fluorogenic reagents. II. Ring-fused 4-diazomethylcoumarins

Doi:10.1248/cpb.34.390
(1986)
Copper-Catalyzed Photoinduced Enantioselective Dual Carbofunctionalization of Alkenes

Doi:10.1021/acs.orglett.0c00071
(2020)
Synthesis of pyrrolizidine alkaloids via 1,3-dipolar cycloaddition involving cyclic nitrones and unsaturated lactones

Doi:10.1016/j.carres.2008.04.029
(2008)
8,10-Dimethyl-7,13-dioxa-10-azaspiro<5,7>tridecane - the first representative of perhydro-1,3-dioxa-6-azocines

Doi:10.1007/BF01151310
(1995)
Enamines; 44. 2-Acyl-1,1-diamino-ethenes. A New Source of Methylketones, β-Keto Amides and β-Keto Esters

Doi:10.1055/s-1986-31711
(1986)
Synthetic studies toward pectenotoxin 2. Part II. Synthesis of the CDE and CDEF ring systems

Doi:10.1021/ol801585j
(2008)

Article Doi

A Method for the Preparation of Stereochemically Defined ψ Pseudodipeptides

DOI: 10.1021/jo00379a019

Source and publish data:

Authors:

Article abstract of DOI:10.1021/jo00379a019

Full text of DOI:10.1021/jo00379a019

Products guided by the article

R&D Labs maybe for 106163-49-9

Relevant to this article

Hot Product