A Method for the Preparation of Stereochemically Defined ψ Pseudodipeptides

DOI: 10.1021/jo00379a019

Source and publish data:

Journal of Organic Chemistry p. 418 - 422 (1987)

Update date:2022-08-04

Topics:: Authors:

TenBrink, Ruth E.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00379a019

A short, stereochemically defined synthesis of (2S,5S)-ψ pseudodipeptides (7a,7b,10) using commercially available, chiral amino acids has been developed.The key step of the synthesis is the intramolecular S_N2 displacement of bromine with alkoxide to give 1,4-oxazin-2-ones (6a,6b,9) that are subsequently hydrolyzed to the desired ψ pseudodipeptides.

Full text of DOI:10.1021/jo00379a019

Products guided by the article

Product name:N-<2-(R)-bromo-3-phenylpropionyl>-L-proline

Cas No:106163-49-9

R&D Labs maybe for 106163-49-9

Aminodiscovery Co.,Ltd.

Contact:+86-535-8888888

Address:No.161 Haishi Rd.
TIC Gums, Inc.

Contact:410-273-7300; 800-221-3953

Address:4609 Richlynn Dr., PO Box 369, Belcamp, MD, 21017-0369, USA
Chongqing KonAo Health Co.,Ltd

Contact:13687578375

Address:wuhan hubei china
NEM CHEMICAL CO.，LTD

website:http://www.NEM.COM.CN

Contact:+86-393-4411771

Address:The west section of shengli Road,Puyang,Henan Province,China
Hisyntech Corporation Limited

Contact:0086-22-23410962

Address:17-201, Ningfuli, Shuishanggongyuandong road,Nankai district, Tianjin, China

Relevant to this article

Studies on stable diazoalkanes as potential fluorogenic reagents. II. Ring-fused 4-diazomethylcoumarins

Doi:10.1248/cpb.34.390
(1986)
Copper-Catalyzed Photoinduced Enantioselective Dual Carbofunctionalization of Alkenes

Doi:10.1021/acs.orglett.0c00071
(2020)
Synthesis of pyrrolizidine alkaloids via 1,3-dipolar cycloaddition involving cyclic nitrones and unsaturated lactones

Doi:10.1016/j.carres.2008.04.029
(2008)
8,10-Dimethyl-7,13-dioxa-10-azaspiro<5,7>tridecane - the first representative of perhydro-1,3-dioxa-6-azocines

Doi:10.1007/BF01151310
(1995)
Enamines; 44. 2-Acyl-1,1-diamino-ethenes. A New Source of Methylketones, β-Keto Amides and β-Keto Esters

Doi:10.1055/s-1986-31711
(1986)
Synthetic studies toward pectenotoxin 2. Part II. Synthesis of the CDE and CDEF ring systems

Doi:10.1021/ol801585j
(2008)

Article Doi

A Method for the Preparation of Stereochemically Defined ψ Pseudodipeptides

DOI: 10.1021/jo00379a019

Source and publish data:

Authors:

Article abstract of DOI:10.1021/jo00379a019

Full text of DOI:10.1021/jo00379a019

Products guided by the article

R&D Labs maybe for 106163-49-9

Relevant to this article

Hot Product