ENANTIO- AND DIASTEREO-CONTROLLED SYNTHESIS OF (+)- AND (-)-ELDANOLIDE BASED ON ASYMMETRIC PINACOL-TYPE REARRANGEMENT

Article abstract of DOI:10.1016/S0040-4039(00)61949-4

Highly enentio- and diastereo-controlled synthesis of chiral pheromone, eldanolide, was accomplished in both enantiomeric forms, via organoaluminium-mediated asymmetric pinacol-type rearrangement followed by stereoselective reduction.