SELECTIVE TRANSFORMATION OF N-t-BUTOXYCARBONYL GROUP INTO N-ALKOXYCARBONYL GROUP via N-CARBOXYLATE ION EQUIVALENT

Article abstract of DOI:10.1016/S0040-4039(01)80883-2

Reaction of a variety of N-t-butoxycarbonyl compounds with t-butyldimethylsilyl trifluoromethanesulfonate afforded the N-t-butyldimethylsilyloxycarbonyl compounds, chemoselectively, which upon treatment with an alkyl or aryl halide provided the corresponding N-alkoxy- or N-aryloxycarbonyl compounds, efficiently.