Optimized and convergent synthesis of potent anti-malarial aminoquinoline compounds: Easy access to analogs

Article abstract of DOI:10.1515/HC.2010.011

Amodiaquine is one of the most active antimalarial 4-aminoquinoline. Previously we have described new analogs of amodiaquine and amopyroquine, in which the hydroxyl group was replaced by various amino groups and identified highly potent compounds. Here we