
Journal of Organic Chemistry p. 2206 - 2208 (1987)
Update date:2022-08-05
Topics:
Nugent, Richard A.
Murphy, Megan
The reaction of β-keto esters and β-diketones with readily accessible 2-halo pyridinium salts in the presence of DBU serves as a rapid and convenient method for the synthesis of substituted indolizines.The use of diethyl malonate as the dicarbonyl component of the reaction enables the preparation of previously undescribed 2-hydroxyindolizines.
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(1986)Doi:10.1016/S0040-4039(00)85385-X
(1986)Doi:10.1039/b808029a
(2008)Doi:10.1246/cl.1986.1029
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(1986)