
Chemical and Pharmaceutical Bulletin p. 1284 - 1287 (1999)
Update date:2022-07-29
Topics:
Takeuchi, Yasuo
Nagao, Yoshiyuki
Toma, Kyoko
Yoshikawa, Yumiko
Akiyama, Teruaki
Nishioka, Hiromi
Abe, Hitoshi
Harayama, Takashi
Yamamoto, Shigeo
Total synthesis of vibrioferrin (1), a siderophore, was achieved via a chiral dibenzyl citrate obtained by optical resolution. The citrate moiety of vibrioferrin was determined to have the R configuration and one of the diastereomeric isomers (1b) of 1 did not exhibit siderophore activity.
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