Synthesis and siderophore activity of vibrioferrin and one of its diastereomeric isomers

DOI: 10.1248/cpb.47.1284

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1284 - 1287 (1999)

Update date:2022-07-29

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Authors:

Takeuchi, Yasuo

Nagao, Yoshiyuki

Toma, Kyoko

Yoshikawa, Yumiko

Akiyama, Teruaki

Nishioka, Hiromi

Abe, Hitoshi

Harayama, Takashi

Yamamoto, Shigeo

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Article abstract of DOI:10.1248/cpb.47.1284

Total synthesis of vibrioferrin (1), a siderophore, was achieved via a chiral dibenzyl citrate obtained by optical resolution. The citrate moiety of vibrioferrin was determined to have the R configuration and one of the diastereomeric isomers (1b) of 1 did not exhibit siderophore activity.

Full text of DOI:10.1248/cpb.47.1284

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