
Tetrahedron p. 4875 - 4886 (1987)
Update date:2022-08-05
Topics:
Solaja, Bogdan
Huguet, Joan
Karpf, Martin
Dreiding, Andre S.
The first synthesis of racemic isoptychanolide (2), a stereoisomer of natural ptychanolide (1), which differs in the configuration of the oxirane function, is reported.The key steps were an α-alkinone cyclisation (5 <*> 4, gas phase flow thermolysis at 62
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(1987)