Journal of Medicinal Chemistry p. 1426 - 1433 (1987)
Update date:2022-08-04
Topics: In vitro Chromatography Mass spectrometry (MS) Nuclear Magnetic Resonance (NMR) Enzyme inhibition in vivo Purification Structure-Activity Relationship (SAR) Biological Activity Synthetic Chemistry Spectroscopic Analysis Cell-based assay Phosphonate Phosphate
Nguyen
Niesor
Bentzen
New diphosphonate compounds and related derivatives were synthesized and investigated for their activity in specifically inducing plasma high density lipoproteins (HDL) and high density lipoprotein cholesterol (HDL-C) in normal rats. The screening of nume
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(1957)