gem-Diphosphonate and gem-phosphonate-phosphate compounds with specific high density lipoprotein inducing activity

DOI: 10.1021/jm00391a027

Source and publish data:

Journal of Medicinal Chemistry p. 1426 - 1433 (1987)

Update date:2022-08-04

Topics: In vitro Chromatography Mass spectrometry (MS) Nuclear Magnetic Resonance (NMR) Enzyme inhibition in vivo Purification Structure-Activity Relationship (SAR) Biological Activity Synthetic Chemistry Spectroscopic Analysis Cell-based assay Phosphonate Phosphate

Authors:

Nguyen Nguyen

Niesor Niesor

Bentzen Bentzen

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00391a027

New diphosphonate compounds and related derivatives were synthesized and investigated for their activity in specifically inducing plasma high density lipoproteins (HDL) and high density lipoprotein cholesterol (HDL-C) in normal rats. The screening of nume

Full text of DOI:10.1021/jm00391a027

Products guided by the article

Product name:(3,4,5-Trimethoxy-benzoyl)-phosphonic acid dimethyl ester

Cas No:108834-52-2

R&D Labs maybe for 108834-52-2

uni source industries limited

Contact:86 21 3772 9386

Address:Rm.1803,Starry Bldg.1,1505 Meijiabang Road,Shanghai 201620 China
Qingzhou Baibang import and export co.,Ltd

Contact:+86-536-3265899

Address:No.338, Tuoshan Road
Shanghai Dynamic Industrial Co.,Ltd.

website:http://www.shdynamic.com

Contact:86-021 3392 6680

Address:Room 805 Information Tower, No.1403 Minsheng Road, Pudong New Area, Shanghai 200135, P. R. China
Joyochem Co., Ltd.

website:https://sdjingyuan.lookchem.com/

Contact:86-531-82687998

Address:Factory Building 11, Jinan Comprehensive free trade zone, Shandong, China
CHINA MEHECO CORPORATION

Contact:+86-10-67147360/67107388

Address:No.18 Guangming Zhongjie, Chongwen District, Beijing, 100061, China

Relevant to this article

A mild, selective method for preparation of vicinal fluoro ethers using 'F-Teda-BF₄

Doi:10.1016/S0040-4039(00)79977-1
(1994)
Stereochemical fate of C-26 and C-27 during the conversion of isofucosterol to sitosterol and of 24-methylenecholesterol to campesterol and dihydrobrassicasterol in Oryza sativa cell cultures

Doi:10.1016/S0031-9422(00)00122-9
(2000)
Methylenecyclopropane Rearrangement as a Probe for Free Radical Substituent Effects. ?^. Values for Commonly Encountered Conjugating and Organometallic Groups

Doi:10.1021/jo00391a015
(1987)
Ionic Liquid Catalyzed One-Pot Synthesis of 2H-Pyridazino[1,2-a]indazole-1,6,9(11H)-triones Via Three-Component Reaction under Solvent-Free Conditions

Doi:10.1002/jhet.1736
(2016)
Concise asymmetric synthesis of (+)-febrifugine utilizing trans-selective intramolecular conjugate addition

Doi:10.1055/s-2008-1067271
(2008)
Doi:10.1021/ja01578a034
(1957)

Article Doi