METAL-HYDRIDE REDUCTION OF ISOXAZOLINE-3-CARBOXYLATE ESTERS

DOI: 10.1016/S0040-4020(01)82075-5

Source and publish data:

Tetrahedron p. 5267 - 5272 (1986)

Update date:2022-08-03

Topics: Ester Reduction Experimental terms Metal hydride

Authors:

Caldirola, Patrizia

De Amici, Marco

De Micheli, Carlo

Wade, Peter A.

Price, David T.

Bereznak, James F.

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Article abstract of DOI:10.1016/S0040-4020(01)82075-5

The reduction of a series of isoxazoline-3-carboxylate esters with sodium borohydride gave 3-(hydroxymethyl)isoxazolines in 34-98percent yield.Reduction with DIBAH gave isoxazoline-3-carboxaldehydes in 63 and 85percent yields for the two reactions studied

Full text of DOI:10.1016/S0040-4020(01)82075-5

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