3-Pyrroline N-oxide bis(carbamate) tumor inhibitors as analogues of indicine N-oxide

DOI: 10.1021/jm00394a036

Source and publish data:

Journal of Medicinal Chemistry p. 2144 - 2147 (1987)

Update date:2022-09-26

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Authors:

Anderson

Milowsky

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Article abstract of DOI:10.1021/jm00394a036

The 2,3-bis[[(N-methylcarbamoyl)oxy]methyl]-3-pyrroline 1-oxide 5 was synthesized and tested in the murine P388 lymphocytic leukemia model. The compound showed significant reproducible activity was was more potent than indicine N-oxide. 1-Methyl-2-phenyl-

Full text of DOI:10.1021/jm00394a036

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