Nα-Fmoc-protected ω-azido- and ω-alkynyl-L- amino acids as building blocks for the synthesis of "clickable" peptides

Article abstract of DOI:10.1002/ejoc.200800717

The growing interest in the 1,4-disubstituted-1,2,3-triazolyl moiety as an amide bond surrogate and its formation through very mild, chemoselective, and bioorthogonal Cu^I-catalyzed Huisgen 1,3-dipolar [3+2] cycloaddition of an alkynyl to an azi