Tandem nucleophilic substitution-1,3-dipolar cycloaddition reactions of oximes with alkyl halides and dipolarophiles

Article abstract of DOI:10.1016/S0040-4039(00)88763-8

Inter-or intra-molecular N-alkylation of oximes or their alkali metal salts furnishes nitrones which can be trapped by activated and non-activated dipolarophiles in inter- and intra-molecular cycloaddition reactions in good yield.