Synthetic Studies toward Ciguatoxin. Stereocontrolled Construction of the KLM Ring Fragment

DOI: 10.1021/jo00083a008

Source and publish data:

Journal of Organic Chemistry p. 715 - 717 (1994)

Update date:2022-07-29

Topics:

Authors:

Sasaki, Makoto

Inoue, Masayuki

Tachibana, Kazuo

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Article abstract of DOI:10.1021/jo00083a008

The first stereoselective synthesis of the KLM ring fragment of ciguatoxin is reported including as a key step 7-endo selective cyclization of epoxy alcohol to construct a fully substituted oxepane ring (12 -> 13).

Full text of DOI:10.1021/jo00083a008

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