Carbamate ester derivatives as potential prodrugs of the presynaptic dopamine autoreceptor agonist (-)-3-(3-hydroxyphenyl)-N-propylpiperidine

DOI: 10.1021/jm00394a014

Source and publish data:

Journal of Medicinal Chemistry p. 2008 - 2012 (1987)

Update date:2022-08-04

Topics:

Authors:

Thorberg

Berg Berg

Lundstrom

Pettersson

Wijkstrom

Sanchez Sanchez

Lindberg

Nilsson Nilsson

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00394a014

Twenty derivatives bearing substituents on the phenolic function of (-)-3-(3-hydroxyphenyl)-N-propylpiperidine [(-)-3-PPP] were synthesized and tested as prodrugs. The carbamate ester derivatives were found to be the most suitable prodrugs, and especially

Full text of DOI:10.1021/jm00394a014

Products guided by the article

Product name:(-)-3-<3-<<(4-ethoxyphenyl)carbamoyl>oxy>phenyl>-N-propylpiperidine

Cas No:110174-92-0

R&D Labs maybe for 110174-92-0

Nowa pharmaceuticals Co., LTD

Contact:86-512-69362780,69362785

Address:No.69 Weixin Road,Weiting Town,Suzhou Industrial Park
Xi'an Herbland Tech Inc.

Contact:+86-29-88710656

Address:South Tai bai Road, High Tech Development Zone, Xi'an China
Hangzhou Haichem Co.,Ltd.

Contact:+86-571-86025531 / 86024803

Address:1218-24 Guangyin Mansion,42 Fengqi East Road
Shandong Yubin Chemical CO.,LTD

website:http://www.yukaichem.com/en.html

Contact:+86-536-8865336

Address:binhai economic development zone，262737 shangdong，china
Hubei Lingsheng Pharmaceuticals Co., Ltd.

Contact:+86-0710-3538058

Address:Xiangyang City Xiangcheng Economic Development Zone, Hubei Province

Relevant to this article

Chelation-assisted carbon-halogen bond activation by a rhodium(I) complex

Doi:10.1021/ic801878e
(2009)
Stable adducts of a dimeric magnesium(I) compound

Doi:10.1002/anie.200803960
(2008)
AN ANIONIC 3+2 CYCLIZATION-ELIMINATION ROUTE TO CYCLOPENTENES

Doi:10.1016/S0040-4039(00)85360-5
(1986)
Supramolecular helical fluid columns from self-assembly of homomeric dipeptides

Doi:10.1002/chem.200801607
(2008)
Conformational Preference in 1,3-Dithianes Containing 2-Phosphoryl, -(thiophosphoryl), and -(selenophosphoryl) groups. Chemical and Crystallographic Implications of the Nature of the Anomeric Effect

Doi:10.1021/jo00086a016
(1994)
Identification and Synthesis of 2-Heptanethiol, a New Flavor Compound Found in Bell Peppers

Doi:10.1021/jf035008h
(2004)

Article Doi