SYNTHESIS AND EVALUATION OF POTENTIAL GLUTAMINE ANTAGONISTS

DOI: 10.1016/0223-5234(87)90047-X

Source and publish data:

European Journal of Medicinal Chemistry p. 179 - 186 (1987)

Update date:2022-08-05

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Authors:

Lachance, Bernard

Salvador, Romano L.

Simon, David Z.

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Article abstract of DOI:10.1016/0223-5234(87)90047-X

Ten acetylenic esters, amides and N_δ-alkynyl derivatives of serine, 2,3-diaminopropanoic acid and glutamine were prepared as potential phosphoribosyl pyrophosphate amidotransferase (EC 2.4.2.14) inhibitors as well as anti-tumor agents against e

Full text of DOI:10.1016/0223-5234(87)90047-X

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