Enantioselective approach to the steroid skeleton by conjugate addition of alkenylcopper-phosphine complexes. Total syntheses of estrone methyl ether and its 7-alkylated derivative

Article abstract of DOI:10.1016/S0040-4039(00)89052-8

Enantioselective syntheses of estrone methyl ether and its 7-alkylated derivative by the conjugate addition of alkenylcopper-phosphine complexes and discussions for the diastereoselectivity in the intramolecular Diels-Alder reaction of the o-quinodimethane derivative on the basis of MM2 transition structure models are presented.