Journal of Organic Chemistry p. 5143 - 5150 (1987)
Update date:2022-08-04
Topics:
Melillo, David G.
Larsen, Robert D.
Mathre, David J.
Shukis, William F.
Wood, Alfred W.
Colleluori, Joseph R.
Two enantioselective routes were developed to prepare chiral amino acid derivative 4.The key step in the first route was catalytic hydrogenation of acrylate derivative 3 using chiral rhodium catalysts.In the second route the key step was acylation of 2-ch
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