Induction of Asymmetry by a Remote Chiral Center in the Amide Acetal Claisen Rearrangement

Article abstract of DOI:10.1021/ja00256a026

The room-temperature preparation of N,O- and N,S-ketene acetals, which undergo facile sigmatropic rearrangement, from amides and thioamides has made possible the use of a remote chiral auxiliary to induce relative asymmetry in the rearrangement.N-Propiony