SYNTHESE REGIOSPECIFIQUE D'UN DINUCLEOSIDE PONTE : (O6-DESOXYGUANOSINYL)-1 (N4-DESOXYCYTIDYL)-2 ETHANE

DOI: 10.1016/S0040-4039(01)91006-8

Source and publish data:

Tetrahedron Letters p. 3195 - 3198 (1984)

Update date:2022-08-04

Topics:

Authors:

Maggio, Annie-Francoise

Lucas, Marc

Barascut, Jean-Louis

Imbach, Jean-Louis

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Article abstract of DOI:10.1016/S0040-4039(01)91006-8

Appropriate protected deoxyguanosine and deoxyuridine derivatives, respectively activated at O⁶ and O⁴ positions by the 3-nitro 1,2,4-triazol 1-yl group, were reacted with ethylene glycol, ethylenediamine or ethanolamine to give monoalkylated nucleosides or cross-linked dimers or cross-linked dinucleosides.

Full text of DOI:10.1016/S0040-4039(01)91006-8

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