SYNTHETIC STUDIES ON (+)-APLASMOMYCIN. 2. STEREOSELECTIVE SYNTHESIS OF COREY'S KEY INTERMEDIATE, A FORMAL TOTAL SYNTHESIS

Article abstract of DOI:10.1016/S0040-4039(00)87805-3

The C-3 - C-11 segment 2 of (+)-aplasmomycin was synthesized stereoselectively starting from (+)-pantolactone (4) and the C-3 - C-17 segment 3 was synthesized via coupling of 1 and 2.