Synthesis of new 2,4-diamino-5-benzylpyrimidines active against various bacterial species

DOI: 10.1016/0223-5234(92)90007-N

Source and publish data:

European Journal of Medicinal Chemistry p. 237 - 244 (1992)

Update date:2022-08-02

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Authors:

Kansy, M

Seydel, JK

Wiese, M

Haller, R

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Article abstract of DOI:10.1016/0223-5234(92)90007-N

New inhibitors of mycobacterial dihydrofolate reductase (DHFR) have been developed.These compounds show high inhibitory activities against Gram-negative and mycobacterial DHFR exceeding that for the commercially available DHFR blockers.Amongst these compo

Full text of DOI:10.1016/0223-5234(92)90007-N

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