Synthesis of new 2,4-diamino-5-benzylpyrimidines active against various bacterial species

DOI: 10.1016/0223-5234(92)90007-N

Source and publish data:

European Journal of Medicinal Chemistry p. 237 - 244 (1992)

Update date:2022-08-02

Topics:

Authors:

Kansy, M

Seydel, JK

Wiese, M

Haller, R

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0223-5234(92)90007-N

New inhibitors of mycobacterial dihydrofolate reductase (DHFR) have been developed.These compounds show high inhibitory activities against Gram-negative and mycobacterial DHFR exceeding that for the commercially available DHFR blockers.Amongst these compo

Full text of DOI:10.1016/0223-5234(92)90007-N

Products guided by the article

Product name:K-122

Cas No:111452-95-0

R&D Labs maybe for 111452-95-0

Qingdao Kingway Pharmtech Co., Ltd.

Contact:86-532-87118899

Address:No. 88, Middle Haixi Road, Jiaonan City, Qingdao, China
Quzhou Ruiyuan chemical Co., Ltd

Contact:+86-570-3039321/3039361/3039308

Address:18# Huayang Road,Quzhou High-tech Industrial Park, Zhejiang China.
Hangzhou Showland Technology Co., Ltd.

Contact:86-571-88920516

Address:ROOM2118,NO.553,WENSAN ROAD,HANGZHOU,CHINA
Hebei Lead Bio-Chemicals Co., Ltd.

website:http://www.ldbiochem.com

Contact:+86-311-87826503

Address:481, Heping West Road, Shijiazhuang,China
Nanjing Raise Pharmatech Co., Ltd

website:http://www.raisechem.com

Contact:+86-25-58649566

Address:B381,No.606,Ningliu Road,Jiangbei New Area,Nanjing,Jiangsu Province,China

Relevant to this article

STAGE SYNTHESIS OF THREE MODIFIED PRENOLS

Doi:10.1007/BF00959372
(1987)
Peri Fluoro Steric Effects: Syntheses and Comparative Acid-Catalyzed Isomerization of the 8-, 9-, and 11-Fluoro-1,2,3,4-tetrahydro-7,12-dimethylbenz anthracenes to Exo Methylene Tautomers

Doi:10.1021/jo00237a023
(1988)
Kinetics and Mechanism of Acid-Catalyzed Oxidation of Substituted Toluenes by Pyridinium Fluorochromate

Doi:10.1246/bcsj.59.3217
(1986)
Synthesis of pyrazoles, diazepines, enaminones, and enamino esters using 12-tungstophosphoric acid as a reusable catalyst in water

Doi:10.1055/s-0028-1083169
(2008)
REGIOSELECTIVITY OF DIELS-ALDER ADDITIONS OF 1-ACETYLVINYL ARENECARBOXYLATES

Doi:10.1016/S0040-4039(01)81009-1
(1987)
Design, synthesis, and biological evaluation of new cinnamic derivatives as antituberculosis agents

Doi:10.1021/jm101510d
(2011)

Article Doi