THE SYNTHESIS AND STRUCTURE OF β-ENAMINO SULPHOXIDES

Article abstract of DOI:10.1016/S0040-4020(01)87366-X

Parent aliphatic and aromatic β-enamino sulphoxides bearing secondary and tertiary alkylamino residues are synthesized by mixing of alkylamine hydrochlorides with metallated enolates of the β-oxosulphoxides in methanol.The latter compounds are obtained in very good yields from metallated sulphoxides and tertiary amides at room temperature in tetrahydrofuran.The majority of the products have enaminic structures in chloroform solution, and E and Z configurations with tertiary and secondary β-alkylamino residues, respectively.