Effects of D-Amino Aids Substitution on Antagonist Activities of Angiotensin II Analogues

DOI: 10.1021/jm00398a005

Source and publish data:

Journal of Medicinal Chemistry p. 510 - 516 (1988)

Update date:2022-08-03

Topics:

Authors:

Samanen, J.

Narindray, D.

Adams, W.

Cash, T.

Yellin, T.

Regoli, D.

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Article abstract of DOI:10.1021/jm00398a005

The sinthesis and biological activities of angiotensin II (AII) analogues are desscribed and compared to the literature.D-Amino acid substitution was employed to search for novel AII antagonists that also display reduced partial agonist activity.Substitut

Full text of DOI:10.1021/jm00398a005

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