Chemistry Letters p. 1627 - 1630 (1987)
Update date:2022-07-30
Topics:
Gotoh, Takeshi
Koyama, Tanetoshi
Ogura, Kyozo
Dimethylallyl- and geranyl methylenediphosphonate are active as artificial substrates for farnesyl diphosphate synthase to give E,E-farnesyl diphosphate.By comparing the kinetic data obtained with the analogues and the natural substrates, the significance of the diphosphate moiety of the substrates of prenyltransferase is discussed.
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