Synthesis of (aminocarbene)chromium(0) complexes by the reaction of Na2Cr(CO)5 with amides in the presence of trimethylsilyl chloride

Article abstract of DOI:10.1021/om00093a021

Addition of trimethylsilyl chloride to a mixture of Na₂Cr(CO)₅ and a variety of tertiary amides produced (aminocarbene)pentacarbonylchromium(0) complexes in fair to excellent yield. The procedure developed is a rapid, convenient, one-pot process and permits the synthesis of carbene complexes not readily available by other synthetic routes. These carbene complexes have potential application in the synthesis of β-lactams and α-amino acids.