Amino Acids and Peptides; 60. Synthesis of Biologically Active Cyclopeptides; 10. Synthesis of 16 Structural Isomers of Dolastatin 3; II: Synthesis of the Linear Educts and the Cyclopeptides

Article abstract of DOI:10.1055/s-1987-27900

Sixteen isomers of the cancerostatic cyclopeptide Dolastatin 3 of marine origin are synthesized.The proposed structure of Dolastatin 3 is proved to be not correct.