Tetrahedron Letters p. 1287 - 1290 (1987)
Update date:2022-08-03
Topics:
Nohara, Fujio
Nishii, Masahiro
Ogawa, Kazuo
Isono, Kiyoshi
Ubukata, Makoto
et. al
The first synthesis of the antitumor antibiotic guanine 7-oxide (VI) has been achived via a 4-step route starting from phenacyl bromide (I) and the nitropyrimidone III and proceeding through the intermediates IVe and Ve.
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