Journal of the American Chemical Society p. 3979 - 3982 (1988)
Update date:2022-09-26
Topics:
Roush, William R.
Banfi, Luca
The chiral auxiliary designated in the title was designed as a probe of our previously suggested mechnism of asymmetric induction with tartrate allylboronates 1-3, namely that n/n electronic repulsive interactions between electron pairs on the aldehydic oxygen atom and an ester carbonyl disfavor transition-state C relative to A.The results reported for the new reagent 5 strongly support this thesis and suggest that the convergence of functional groups toward a metal center can be an exceedingly useful strategy for achieving a topological bias in the enantioselective functionalization of a carbonyl group.
View MoreContact:13120882795;+86-21-34621078;+86-021-31122318
Address:Suite 2,No.2715 Longwu Road
Contact:86-512-69362780,69362785
Address:No.69 Weixin Road,Weiting Town,Suzhou Industrial Park
Jinan Baozhao Pharmaceutical Co., Ltd
Contact:0086-531-86397156 82371858 82371868
Address:Huaneng Road, Jinan, Shandong ,China
Shanghai Mintchem Development ., Ltd
Contact:0086 21 5190 8570
Address:R602,4#,89Nong, Mudan Road Pudong Shanghai China
Tianjin Tongde Biological Technology Co., Ltd.
Contact:86-22-23309138
Address:Room 402, bulidingE3 Detection certification park, XiQingDistrict, Tianjin City
Doi:10.1135/cccc19931607
(1993)Doi:10.1055/s-2000-7597
(2000)Doi:10.1021/jo00076a047
(1993)Doi:10.1021/ja00076a091
(1993)Doi:10.1016/j.tet.2013.11.080
(2014)Doi:10.1039/DT9930003081
(1993)