Highly Effective Dephosphorylation of F-1-Alkenyl Phosphates with Copper Halide-Lithium Aluminium Hydride Reagent: A New Access to 1-Hydryl-F-alkyl Ketones from F-Alkyl Ketones

Article abstract of DOI:10.1016/S0022-1139(00)83092-4

1-Substituted F-1-alkenyl phosphates, readily available from F-alkyl ketones and diethyl phosphite, undergo the dephosphorylation by the action of copper(I) or copper(II) bromide and lithium aluminium hydride at -78 deg C followed by hydrolysis to give th