PYRIDINE AND REDUCED PYRIDINE ANALOGUES OF 1,2,5-THIADIAZOLES AS HISTAMINE H2-RECEPTOR ANTAGONISTS

DOI: 10.1016/0223-5234(87)90269-8

Source and publish data:

European Journal of Medicinal Chemistry p. 319 - 324 (1987)

Update date:2022-07-30

Topics:

Authors:

Agrawal, Vijai K.

Knaus, Edward E.

McNeill, John H.

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Article abstract of DOI:10.1016/0223-5234(87)90269-8

A series of 4-amino and 4-methylamino-3-<2-(pyridylmethylthio)ethylamino>-1,2,5-thiadiazole-1-oxides 6-11 and 1,1-dioxides 12-17 were prepared.Pharmacological testing using the histamine induced guinea pig atria chronotropic response indicated that the py

Full text of DOI:10.1016/0223-5234(87)90269-8

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Product name:1(2H)-Pyridinecarboxylic acid, 3-[[[2-[[4-(methylamino)-1,2,5-thiadiazol-3-yl]amino]ethyl]thio]methyl]-, phenyl ester, S,S-dioxide

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