Synthesis of 6A,6X-Di-O-(p-tosyl)-γ-cyclodextrins and Their Structural Determination through Enzymatic Hydrolysis of 3A,6A;3X,6X-Dianhydro-γ-cyclodextrins

Article abstract of DOI:10.1021/jo00244a018

6^A,6^X-Di-O-(p-tosyl)-γ-cyclodextrins (X = B, C, D, and E) were prepared by the reaction of γ-cyclodextrin and p-tosyl chloride in pyridine and isolated by reversed-phase column chromatography.From the results of Taka amylolyses of 3^A,6^A;3^X,6^X-dianhydro-γ-cyclodextrins which were obtained from the corresponding ditosylates, the regiochemistry of the ditosylates was determined.