Tetrahedron p. 825 - 834 (1987)
Update date:2022-07-31
Topics:
Niwa, Haruki
Hasegawa, Takashi
Ban, Norikazu
Yamada, Kiyoyuki
The first total synthesis of the two biooxidation products of patchouli alcohol (2), (+/-)-hydroxy patchouli alcohol (3) and the corresponding (+/-)-carboxylic acid 4, has been achieved in highly stereocontrolled manners.Synthesis of (+/-)-norpatchoulenol (1), the real odoriferous substance of patchouli oil, has been accomplished by the biogenetic route via (+/-)-3 and (+/-)-4.
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Doi:10.1016/S0040-4039(00)96485-2
(1987)Doi:10.1055/s-1987-28100
(1987)Doi:10.1016/j.poly.2008.11.012
(2009)Doi:10.1021/ol9002509
(2009)Doi:10.1246/cl.1987.1345
(1987)Doi:10.1039/jr9580001367
(1958)