Synthesis and X-ray structure of a 1,2,3,6-tetrahydropyridine-based phenylalanine mimetic

Article abstract of DOI:10.1016/S0040-4039(98)02125-X

A ring-closing metathesis reaction on methyl (2R)-(N-allyl-N- benzoylamino)-2-benzylpent-4-enoate 5, prepared as a single isomer from L- phenylalanine, gave a conformationally restricted 1,2,3,6- tetrahydropyridine-based phenylalanine mimetic 6 in good yi