(Imidazopyrimidin-2-yl)phenylmethanones and Related Compounds as Potential Nonsedative Anxiolytics

DOI: 10.1021/jm00401a025

Source and publish data:

Journal of Medicinal Chemistry p. 1220 - 1226 (1988)

Update date:2022-09-26

Topics:

Authors:

Clements-Jewery, Stephen

Danswan, Geoffrey

Gardner, Colin R.

Matharu, Saroop S.

Murdoch, Robert

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00401a025

Several series of heterocyclic carboxylic esters were found to be active in the benzodiazepine receptor binding assay, a typical example being ethyl 7-ethyl-5-methoxyimidazo<1,2-a>quinoline-2-carboxylate (4b) with an IC₅₀ of 150 nM.The correspo

Full text of DOI:10.1021/jm00401a025

Products guided by the article

Product name:(5-Ethoxy-8,9-dihydro-6H-7-thia-3,4,9b-triaza-cyclopenta[a]naphthalen-2-yl)-phenyl-methanone

Cas No:114095-13-5

R&D Labs maybe for 114095-13-5

Nanjing lanbai chemical Co.,Ltd.

Contact:+86-25-85499326

Address:Room 908, 9F Taiyue Building,No.285 Heyan Road
Tianjin Ingenochem Technology Co.,Ltd

Contact:+86-22-23677060

Address:Hitech Green Industry Park K2-9-602, Nankai district
EGBERT CORPORATION

Contact:+86 18616952870

Address:Area
Huangshi Shennong Chemical Technology Co., Ltd

Contact:+86-714-3072290

Address:Eastern industrial park , Tieshan district , Huangshi city ,Hubei province , China
Qingdao Kingway Pharmtech Co., Ltd.

Contact:86-532-87118899

Address:No. 88, Middle Haixi Road, Jiaonan City, Qingdao, China

Relevant to this article

KOENIGS-KNORR GLYCOSIDATIONS WITH 3,4,6-TRI-O-ACETYL-2-DEOXY-2-<(4,4-DIMETHYL-2,6-DIOXOCYCLOHEXYLIDENEMETHYL)-AMINO>-α-D-GLUCOPYRANOSYL BROMIDE

Doi:10.1016/0008-6215(87)80134-9
(1987)
Three in one: prototropy-free highly stable AADD-type self-complementary quadruple hydrogen-bonded molecular duplexes with a built-in fluorophore

Doi:10.1039/C6CC09478C
(2017)
Internal Thioaldehyde Trapping by Enes and Dienes

Doi:10.1021/jo00245a018
(1988)
Designed Water-Soluble Macrocyclic Esterases: From Nonproductive to Productive Binding

Doi:10.1021/jo00247a017
(1988)
Cryptophycin-39 unit a precursor synthesis by a tandem Shi epoxidation and lactonization reaction of trans-styryl acetic acid

Doi:10.1055/s-0028-1087541
(2009)
Concise strategy for the synthesis of elevenmembered and ansa-bridged thirteen-membered lactone macrolides by ring-closing metathesis reaction

Doi:10.1139/V08-171
(2009)

Article Doi