(Imidazopyrimidin-2-yl)phenylmethanones and Related Compounds as Potential Nonsedative Anxiolytics

DOI: 10.1021/jm00401a025

Source and publish data:

Journal of Medicinal Chemistry p. 1220 - 1226 (1988)

Update date:2022-09-26

Topics:

Authors:

Clements-Jewery, Stephen

Danswan, Geoffrey

Gardner, Colin R.

Matharu, Saroop S.

Murdoch, Robert

et al. et al.

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Article abstract of DOI:10.1021/jm00401a025

Several series of heterocyclic carboxylic esters were found to be active in the benzodiazepine receptor binding assay, a typical example being ethyl 7-ethyl-5-methoxyimidazo<1,2-a>quinoline-2-carboxylate (4b) with an IC₅₀ of 150 nM.The correspo

Full text of DOI:10.1021/jm00401a025

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