Efficient and Flexible Syntheses of Paraconic Esters and Other Highly Substituted Furanone Derivatives from Methyl 2-Siloxycyclopropanecarboxylates

Article abstract of DOI:10.1021/jo00246a010

Deprotonation of methyl 2-siloxycyclopropanecarboxylates 1 with lithium diisopropylamide and reaction of the resulting enolates with carbonyl compounds produce trifunctional cyclopropane derivatives.These primary adducts can only be isolated with good yie