Magnetic Resonance in Chemistry p. 696 - 706 (1987)
Update date:2022-08-04
Topics:
Banting, Lee
Crabb, Trevor A.
In contrast to perhydro-oxazolo<3,4-a>pyridine and perhydrothiazolo<3,4-a>pyridine, which adopt equilibria in CDCl3 solution at room temperature containing ca 70percent trans-fused conformers in equilibria with O- or S-inside cis-fused conformers, 2-alkylperhydroimidazolo<3,4-a>pyridines are found to adopt equilibria containing >98percent trans-fused conformers.Comparison of NMR parameters of 2-methylperhydroimidazolo<3,4-a>pyridine with those of the two isomers of 1,2-dimethylperhydroimidazolo<3,4-a>pyridine indicates an equilibrium for the former compound between the two trans-fused conformers, with ca 83percent of that conformation containing a transarrangement of nitrogen lone pairs of electrons.These observations are explained in terms of the generalized anomeric effect.KEY WORDS Perhydroimidazolo<3,4-a>pyridine Conformational equilibria 1H and 13C NMR
View Moreshanghai Tauto Biotech Co., Ltd
website:http://www.tautobiotech.com/en/index.htm
Contact:+86-21-51320588 ext. 8025
Address:No. 326, Aidisheng Rd , Zhangjiang Hi-tech Park, Shanghai , P.R.CHINA
Contact:+8613400661290
Address:No 908,Kangwan Rd, Liuyang Economic
Xinjiang Zhongtai Chemical Co., Ltd.
Contact:+86-991-8788172
Address:NO.78 XISHAN RD.URUMQI，CHINA
Xiamen Hisunny Chemical Co.,Ltd
website:http://www.hisunnychem.com
Contact:+86-592-3327115
Address:Unit 603,No.879,Xiahe Road,Meixin Building,Xiamen,China
Kaymossy BioChem Tech Co., Ltd
website:http://www.kaimosi.com
Contact:0571-87191913/0571-87199097
Address:Room 215, Building 3rd, No.288 Ningxia Road, Qingdao city, China
Doi:10.1021/om00097a016
(1988)Doi:10.1016/j.carres.2008.12.015
(2009)Doi:10.1021/jo9001867
(2009)Doi:10.1002/jhet.202
(2009)Doi:10.1002/adsc.201801436
(2019)Doi:10.1016/j.tetlet.2009.02.033
(2009)
