Journal of the American Chemical Society p. 4019 - 4022 (1988)
Update date:2022-07-30
Topics:
Hoffman, Robert V.
Shankweiler, Jean M.
A series of amines with various alkyl and aryl substituents at C-1 were converted to the corresponding N-(arylsulfonoxy)amines, which served as precursors for base-promoted, imine-forming elimination.By varying the bases used to promote the elimination and by varying the leaving groups attached to nitrogen, the Broensted parameters β and βlgCH3 were determined.These were used to locate the transition state on the More O'Ferrall-Jencks energy surface for elimination.Substituents were found to influence the structure of the activated complex markedly.Resonance effects were most important, while inductive effects had little influence .
View MoreJinan Chenghuishuangda Chemical CO.,Ltd
website:http://www.jnchsd.com
Contact:+86-531-58897082
Address:No.2350, Kaituo Road, High-tech Development District, Jinan City, Shandong, China
RongCheng K&S Chemical Co.,Ltd
Contact:0631-7336369
Address:rongcheng ,shandong province china
HANGZHOU YUNUO CHEMICAL CO.,LTD
website:http://www.yunuochem.com
Contact:0571-83715115
Address:hangzhou
ShangHai Original Economy-Trade Develop Co.,Ltd.,
Contact:86-21-68552131
Address:shanghai
Contact:+86-574-87065746
Address:10th Floor, No.787 Baizhang East Road,
Doi:10.1016/j.tet.2014.05.014
(2014)Doi:10.1016/j.tetlet.2009.11.095
(2010)Doi:10.1039/c9ob01992h
(2019)Doi:10.1016/j.ica.2008.07.015
(2009)Doi:10.1021/ol900240s
(2009)Doi:10.1016/j.ejmech.2008.09.001
(2009)