Journal of Medicinal Chemistry p. 1839 - 1846 (1988)
Update date:2022-08-05
Topics:
Buhlmayer
Caselli
Fuhrer
Goschke
Rasetti
Rueger
Stanton
Criscione
Wood
A series of renin inhibitors containing the dipeptide transition state mimics (2S,4S,5S)-5-amino-4-hydroxy-2-isopropyl-7-methyloctanoic acid (Leu-(OH)-Val) and (2S,4S,5S)-5-amino-4-hydroxy-2-isopropyl-6-cyclohexylhexanoic acid (Cha-(OH)-Val) was prepared.
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