Bioorganic and Medicinal Chemistry Letters p. 1801 - 1806 (1999)
Update date:2022-07-30
Topics:
Keenan, Richard M.
Miller, William H.
Barton, Linda S.
Bondinell, William E.
Cousins, Russell D.
Eppley, Daniel F.
Hwang, Shing-Mei
Kwon, Chet
Lago, M. Amparo
Nguyen, Thomas T.
Smith, Brian R.
Uzinskas, Irene N.
Yuan, Catherine C. K.
A peptide RGD analog containing a novel 2-aminopyridine arginine mimetic was discovered to have good affinity and selectivity for the vitronectin receptor. Incorporation of the 2-aminopyridine arginine mimetic into the 3- oxo-1,4-benzodiazepine-2-acetic acid integrin antagonist series led to novel and potent nonpeptide vitronectin receptor antagonists with promising levels of oral bioavailability.
View Morezhenjiang runjing high purity chemical co ltd
Contact:+86-511-83361155
Address:No.8.haixi road,international chemical park
Jurong Huaheng Natural Biological Products Factory
website:http://www.risebiochem.com
Contact:+86-13921007726
Address:Chuncheng town,Jurong city,Jiangsu province,China
Contact:+86-13914766747
Address:Floors 21&22, Jin Cheng Tower, No. 216 Middle Longpan Road, Nanjing
Daicel Chiral Technologies (China)CO.,LTD
Contact:021-5046-0086*8
Address:Part C, FL 5, the 16th Building, No. 69, XiYa Road, WaiGaoQiao Free Trade Zone, Shanghai, 200131, P.R.China
Contact:+86+21-58956006 15800617331
Address:402 Room, 150# Cailun Road, Zhangjiang high tech park, Shanghai
Doi:10.1016/j.bmc.2009.02.046
(2009)Doi:10.1021/ja01502a082
(1960)Doi:10.1246/bcsj.61.857
(1988)Doi:10.1021/ol900592b
(2009)Doi:10.1016/j.tet.2009.01.089
(2009)Doi:10.1039/b818445c
(2009)
