Nucleosides. 150. Synthesis and some biological properties of 5-monofluoromethyl, 5-difluoromethyl, and 5-trifluoromethyl derivatives of 2'-deoxyuridine and 2'-deoxy-2'-fluoro-β-D-arabinofuranosyluracil

DOI: 10.1021/jm00403a026

Source and publish data:

Journal of Medicinal Chemistry p. 1642 - 1647 (1988)

Update date:2022-08-04

Topics:

Authors:

Matulic-Adamic

Takahashi

Chou Chou

Gadler Gadler

Price Price

Reddy Reddy

Kalman Kalman

Watanabe

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00403a026

A new synthesis of 5-(monofluoromethyl)- and 5-(difluoromethyl)-2'-deoxy-2'-fluoro-β-D-arabinofuranosyluracil (F-FMAU and F₂-FMAU) is reported. 3',5'-Di-O-(tert-butyldiphenyl)silylated thymidine or FMAU was photochemically brominated with NBS t

Full text of DOI:10.1021/jm00403a026

Products guided by the article

Product name:C₄₁⁽¹⁴⁾CH₄₇F₃N₂O₅Si₂

Cas No:114652-86-7

R&D Labs maybe for 114652-86-7

Hebei Lead Bio-Chemicals Co., Ltd.

website:http://www.ldbiochem.com

Contact:+86-311-87826503

Address:481, Heping West Road, Shijiazhuang,China
Shanghai Hanshare Industry Co.,Ltd.

Contact:86 21 20960688

Address:RM902-903,Building E, Wanda Plaza,No.26,Zhoukang Road, Pudong District, Shanghai, China
jiangsu haian chemical co.,ltd.

Contact:86-513-15851283853

Address:No.99,Changjiang West Road,Haian County,Jiangsu Province,China
GLD peptide scientific lnc.

Contact:21-7631221 15884421033

Address:326 Science and technology,Shanghai,China
Chemvon Biotechnology Co. Ltd.

website:http://www.chemvon.com

Contact:86-21-58550039;86-21-31268550-8004

Address:Suite B-10#, 6999 Chuansha Road, Pudong District, Shanghai 201202, China

Relevant to this article

Tribromo melamine as novel and versatile catalyst for the formylation and acetylation of alcohols

Doi:10.1016/S1872-2067(12)60748-7
(2014)
Carbon-7 Substituted Actinomycin D Analogues as Improved Antitumor Agents: Synthesis and DNA-Binding and Biological Properties

Doi:10.1021/jm00352a023
(1982)
Dda helicase unwinds a DNA-PNA chimeric substrate: Evidence for an inchworm mechanism

Doi:10.1016/j.bmcl.2006.01.013
(2006)
UEBERGANGSMETALL-HETEROALLEN-KOMPLEXE XVII. REAKTIONEN DES AZA-ALLYL-KOMPLEXES (KETENIMIN)Fe2(CO)6 MIT PHOSPHANEN

Doi:10.1016/0022-328X(87)80230-9
(1987)
Copper-catalyzed synthesis of β-haloalkenyl chalcogenides by addition of dichalcogenides to internal alkynes and its application to synthesis of (Z)-tamoxifen

Doi:10.1016/j.tet.2009.01.094
(2009)
Two titanium-catalyzed reaction sequences for syntheses of pyrroles from(E/Z)-Chloroenynes or α-Haloalkynols

Doi:10.1021/ol900522g
(2009)

Article Doi