Journal of Medicinal Chemistry p. 1642 - 1647 (1988)
Update date:2022-08-04
Topics:
Matulic-Adamic
Takahashi
Chou
Gadler
Price
Reddy
Kalman
Watanabe
A new synthesis of 5-(monofluoromethyl)- and 5-(difluoromethyl)-2'-deoxy-2'-fluoro-β-D-arabinofuranosyluracil (F-FMAU and F2-FMAU) is reported. 3',5'-Di-O-(tert-butyldiphenyl)silylated thymidine or FMAU was photochemically brominated with NBS t
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