Nucleosides. 150. Synthesis and some biological properties of 5-monofluoromethyl, 5-difluoromethyl, and 5-trifluoromethyl derivatives of 2'-deoxyuridine and 2'-deoxy-2'-fluoro-β-D-arabinofuranosyluracil

DOI: 10.1021/jm00403a026

Source and publish data:

Journal of Medicinal Chemistry p. 1642 - 1647 (1988)

Update date:2022-08-04

Topics:

Authors:

Matulic-Adamic

Takahashi

Chou Chou

Gadler Gadler

Price Price

Reddy Reddy

Kalman Kalman

Watanabe

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00403a026

A new synthesis of 5-(monofluoromethyl)- and 5-(difluoromethyl)-2'-deoxy-2'-fluoro-β-D-arabinofuranosyluracil (F-FMAU and F₂-FMAU) is reported. 3',5'-Di-O-(tert-butyldiphenyl)silylated thymidine or FMAU was photochemically brominated with NBS t

Full text of DOI:10.1021/jm00403a026

Products guided by the article

Product name:C₄₁⁽¹⁴⁾CH₄₇F₃N₂O₅Si₂

Cas No:114652-86-7

R&D Labs maybe for 114652-86-7

Sichuan Highlight Fine Chemicals Co., Ltd.

Contact:+86-28-8525 1605

Address:A5-102 Airport base,388 West Airport Huang He Zhong Lu,2 Section
EGBERT CORPORATION

Contact:+86 18616952870

Address:Area
QINGDAO HONG JIN CHEMICAL CO.,LTD.

website:http://www.hongjinchem.com

Contact:+86-532-83657313

Address:2ND Building, 8 Shangqing Road, Qingdao, Shandong Province, China.
Oceachem Group Limited

website:http://www.oceanchem-group.com

Contact:86-536-8596048

Address:9th floor,Building B future Plaza, No.88.Fenghuang Street,Weifang,Shandong,China
Kono Chem Co.,Ltd

website:http://www.konochem.com

Contact:86-29-86107037

Address:No.170 West Avenue,Xi’an 710082,China

Relevant to this article

Tribromo melamine as novel and versatile catalyst for the formylation and acetylation of alcohols

Doi:10.1016/S1872-2067(12)60748-7
(2014)
Carbon-7 Substituted Actinomycin D Analogues as Improved Antitumor Agents: Synthesis and DNA-Binding and Biological Properties

Doi:10.1021/jm00352a023
(1982)
Dda helicase unwinds a DNA-PNA chimeric substrate: Evidence for an inchworm mechanism

Doi:10.1016/j.bmcl.2006.01.013
(2006)
UEBERGANGSMETALL-HETEROALLEN-KOMPLEXE XVII. REAKTIONEN DES AZA-ALLYL-KOMPLEXES (KETENIMIN)Fe2(CO)6 MIT PHOSPHANEN

Doi:10.1016/0022-328X(87)80230-9
(1987)
Copper-catalyzed synthesis of β-haloalkenyl chalcogenides by addition of dichalcogenides to internal alkynes and its application to synthesis of (Z)-tamoxifen

Doi:10.1016/j.tet.2009.01.094
(2009)
Two titanium-catalyzed reaction sequences for syntheses of pyrroles from(E/Z)-Chloroenynes or α-Haloalkynols

Doi:10.1021/ol900522g
(2009)

Article Doi