A CONVENIENT, ONE-STEP, HIGH-YIELD REPLACEMENT OF AN ANOMERIC HYDROXYL GROUP BY A FLUORINE ATOM USING DAST. PREPARATION OF GLYCOSYL FLUORIDES.

Article abstract of DOI:10.1016/S0040-4039(00)98451-X

The anomeric hydroxyl group of various furanose and pyranose hemiacetals can be replaced by a fluorine atom stereoselectively, conveniently, mildly, and on gram-scale using DAST in THF at room temperature.